Yes, supplements like Vitamin D and Folic Acid can boost fertility for both women and men, based on substantial clinical and mechanistic evidence.
Vitamin D and Fertility
- Vitamin D plays a critical role in both female and male reproductive health by participating in ovarian follicle development, hormone regulation, and sperm quality.
- Deficiency is linked to impaired ovulation, lower ovarian reserve, and poorer outcomes in IVF and natural conception.
- Supplementation has been shown to increase clinical pregnancy rates, improve preantral follicle survival, and reduce the rate of chromosomal abnormalities in embryos. Positive effects have been observed regardless of age or body mass index.
Folic Acid and Fertility
- Folic acid is vital for DNA synthesis, cell replication, and oocyte maturation.
- Supplementation regulates ovulation, boosts ovarian reserve and egg quality, and supports successful conception both in natural cycles and assisted reproductive technologies.
- In women with unexplained infertility, folic acid supplementation markedly improved the rate of successful pregnancy without adverse effects.
- Folic acid also enhances sperm quality in men, especially when paired with zinc.
Recommendations and Safety
- Both nutrients are recommended prior to and during conception for optimal fertility and to reduce the risk of pregnancy complications.
- Supplementation should be tailored to individual needs and confirmed via blood tests, ideally under medical supervision.
In summary, Vitamin D and Folic Acid supplementation are effective, evidence-based strategies to increase fertility, improve reproductive outcomes, and support conception for both women and men.
