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The first trimester of pregnancy carries the highest risk from exposure to unripe papaya. During this early phase, the fetus is most vulnerable, and even small amounts of the latex and papain found in unripe or semi-ripe papaya can stimulate uterine contractions, increase the risk of miscarriage, hinder implantation, and weaken vital fetal membranes.

Why the First Trimester Is Most Risky?

Strictly avoid unripe or semi-ripe papaya in all trimesters, but especially during the first trimester, to minimize risks to fetal development and pregnancy outcome.

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